Rosuvastatin Calcium CAS 147098-20-2 Assay 98.5%~102.0% API Factory High Purity

Short Description:

Chemical Name: Rosuvastatin Calcium

CAS: 147098-20-2

Appearance: White to Off-White Powder

Assay: 98.5%~102.0% (Caculated on the Anhydrous Basis)

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Product Detail

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147098-20-2 - Description:

Supply with High Purity and Stable Quality
Rosuvastatin Calcium
CAS: 147098-20-2
Commercial Production

147098-20-2 - Chemical Properties:

Chemical Name	Rosuvastatin Calcium
Synonyms	ZD 4522 Calcium; (E)-6-[4-(4-Fluorophenyl)-6-Isopropyl-2-(Methyl-Methylsulfonyl-amino)pyrimidin-5-yl]-2,4-Dihydroxy-hex-5-Enoate; (6E)-7-{4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(methylsulfonyl) amino]pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid
CAS Number	147098-20-2
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C44H54CaF2N6O12S2
Molecular Weight	1001.14
Melting Point	122℃
Shipping Condition	Shipped Under Ambient Temperature
Brand	Ruifu Chemical

147098-20-2 - Specifications:

Item	Specifications
Appearance	White to Off-White Powder
Specific Rotation	+17.0° ~ +21.0°
Identification	A. Meets the Requirement B. UV: λmax=243nm C. IR: Similar to Reference Substance D. X-Ray: Similar to Reference Substance
Chloride	≤0.10%
Sulphate	≤0.10%
Enantiomer	≤0.15%
Calcium Content	3.5%~4.5%
Related Substances
Diastereomer	≤0.15%
5-Oxo-Rosucastatin	≤0.15%
Photo Degradation 1	≤0.15%
Photo Degradation 2	≤0.15%
Rosuvastatin Lactone	≤0.15%
Rosuvastatin Methyl Ester	≤0.15%
Rosuvastatin Isoamyl Ester	≤0.15%
Any Unknown Impurity	≤0.10%
Total Impurities	≤0.75%
Moisture (K.F)	≤3.0%
Heavy Metal	≤20ppm
Isoamyl Bromide	≤37.5ppm
Residual Solvents
Ethyl Ether	≤300ppm
Acetonitrile	≤410ppm
Isoamyl Alcohol	≤5000ppm
DMF	≤880ppm
Assay	98.5%~102.0% (caculated on the anhydrous basis)
Test Standard	Enterprise Standard; BP/USP/EP Standard
Usage	API

Package & Storage:

Package: Bottle, Barrel, Cardboard drum, 25kg/Barrel, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture

Advantages:

FAQ:

147098-20-2 - Application:

Rosuvastatin Calcium (CAS: 147098-20-2) is an anti-hyperlipidemia drug which belongs to the inhibitor of HMG-CoA reductase successfully developed by the British AstraZeneca company. It is suitable for the treatment of various lipid abnormalities, including hypercholesterolemia, mixed lipid qualitative abnormalities and simple hypertriglyceridemia. Rosuvastatin Calcium (CAS: 147098-20-2) is listed as the strongest and the most comprehensive statins drugs which has entered into market for lipid-lowering and adjustment. Compared with atorvastatin which is currently recognized with the world's best efficacy, it has a better effect of lowering the level of LDL cholesterol and increasing the level of high-density lipoprotein. Moreover, it has a better tolerance, lower side effects and unique pharmacokinetic characteristics with the half-life about 20h.